I don't doubt some California or NY or DC DA's would do what they could to punish a gun owner, even in a defensive shooting scenario.
However, you can offer about anything in defense, subject to the rules of evidence, and I'm sure you could enter your load data as evidence, if you thought it could help, or if it countered some assertion by the DA. If your lawyer can't get that into evidence, your lawyer is an alcoholic who hates life and is taking it out on you.
While of course juries are unpredictable, this thing about the light trigger prosecution and such I've heard about from the time I stepped foot in law school. Of course, I'm in NC, so the whole things seems ultra stupid unless you are in a communist state, at which point the DA may attack you whether you polished a connector or not.
If you intended to shoot the intruder and put a bullet in his body, whether your trigger was 1 ounce or 8 pounds does not seem relevant. If you shot somebody by accident, it does.
I'm wondering, because I haven't looked, is there such a case where somebody went to jail in an otherwise justified shooting simply because they had modded in some way their firearm or made their own ammo. Seems urban-legendish, the kind of "inside baseball" an instructor would like to tell you to help get that class to the advertised amount of hours, along with lots of stories about how they almost had to deploy their firearms as they identified threats in parking lots, malls and while dog walking.
The legal parameters of lethal self defense are set out in this state and they make sense. If you feel in fear of death or serious bodily harm, know your target and only shoot it if you mean to because you will have to answer for that act, 1 pound trigger or 12 pound double action.